Janneke Wrobel

Title: Janneke Wrobel: Innovator in Prostate Cancer Prognosis

Introduction

Janneke Wrobel is a prominent inventor based in Eindhoven, Netherlands, known for her contributions to the field of cancer prognosis. With a total of three patents to her name, her innovative work is focused on methods that improve the understanding and management of prostate cancer.

Latest Patents

Wrobel's latest patents are groundbreaking, aiming to enhance diagnostic methodologies for prostate cancer. One notable invention pertains to "Methods of prostate cancer prognosis," which involves determining the state of prostate cancer through the expression level of phosphodiesterase 4D (PDE4D) variants. This invention not only aids in diagnosing and monitoring prostate cancer but also identifies individuals eligible for specific treatments. Additionally, the patent encompasses products designed for the analysis of PDE4D variants, including pharmaceutical compositions that can modulate the activity and/or expression of these variants.

Another significant contribution is her patent on a "Bioinformatics process for identifying at-risk subject populations." This method calculates a risk score that predicts adverse clinical events over a certain period. By analyzing the activities of various cellular signaling pathways, including the PI3K pathway and others, the invention significantly enhances prognosis related to disease progression, recurrence, metastasis, or mortality. It entails advanced apparatus configurations and computer program instructions to implement its complex functionalities.

Career Highlights

Janneke Wrobel is currently associated with Koninklijke Philips Corporation N.V., a renowned company in the realm of healthcare and technology. Her work within this esteemed organization showcases her commitment to integrating innovative science with practical health solutions.

Collaborations

Wrobel collaborates closely with other esteemed professionals, including her colleagues Anne Godefrida Catharina Van Brussel and Ralf Hoffmann. Their combined expertise strengthens the innovative approaches within her research area, further enhancing the potential impact of their discoveries.

Conclusion

Janneke Wrobel's innovative spirit and dedication to cancer research mark her as a notable inventor in Eindhoven. Her impactful patents not only advance the understanding of prostate cancer but also pave the way for improved therapeutic techniques. Through her collaboration with leading professionals and her work at Philips, Wrobel continues to contribute to critical advancements in healthcare.