The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 28, 2023
Filed:
May. 26, 2016
Koninklijke Philips N.v., Eindhoven, NL;
Ralf Hoffmann, Eindhoven, NL;
Eveline Den Biezen-Timmermans, Eindhoven, NL;
Dianne Arnoldina Margaretha Wilhelmina Van Strijp, Eindhoven, NL;
Anne Godefrida Catharina Van Brussel, Eindhoven, NL;
Marcia Alves De Inda, Eindhoven, NL;
Janneke Wrobel, Eindhoven, NL;
Joannes Baptist Adrianus Dionisius Van Zon, Waalre, NL;
KONINKLIJKE PHILIPS N.V., Eindhoven, NL;
Abstract
The present invention relates to methods for diagnosing, monitoring or prognosticating prostate cancer or the progression state of prostate cancer wherein said method determines the state of the prostate cancer, based on the expression level of phosphodiesterase 4D (PDE4D) variants. The invention further relates to a method of identifying an individual for eligibility for prostate cancer therapy. The invention also relates to products for the analysis of phosphodiesterase 4D (PDE4D) variants as well as pharmaceutical compositions modulating the activity and/or expression of PDE4D variants.