Company Filing History:
Years Active: 2016-2020
Title: Janine Borgaro: Innovator in DNA Modification Technologies
Introduction
Janine Borgaro is a prominent inventor based in Beverly, MA (US), known for her significant contributions to the field of DNA modification technologies. With a total of three patents to her name, she has made remarkable advancements in understanding and manipulating cytosine modifications in DNA.
Latest Patents
One of her latest patents is titled "Compositions and methods for identifying hydroxymethylcytosine in a DNA." This invention provides a non-naturally occurring variant of a wild type restriction enzyme, defined by SEQ ID NO: 20. The variant exhibits at least a two-fold increase in cleavage at 5-β-glucosylhydroxymethylcytosine (5βghmC) compared to methylcytosine relative to the wild type enzyme. Additionally, methods for examining hydroxymethylation of a DNA sample using this variant enzyme are also included. Another notable patent is "Mapping cytosine modifications," which offers methods, compositions, and kits for selectively altering and detecting modified cytosine residues.
Career Highlights
Janine Borgaro is currently employed at New England Biolabs, Inc., where she continues to innovate and develop new technologies in the field of molecular biology. Her work has been instrumental in advancing the understanding of DNA modifications, which have implications in various areas of research and medicine.
Collaborations
Throughout her career, Janine has collaborated with esteemed colleagues, including Shengxi Guan and Zhenyu Zhu. These collaborations have further enhanced her research and contributed to the success of her innovative projects.
Conclusion
Janine Borgaro's work in DNA modification technologies exemplifies her dedication to scientific advancement. Her patents and contributions to the field are paving the way for future innovations in genetic research and applications.