Company Filing History:
Years Active: 1988-1991
Title: Innovations in Antibiotic Production by Janet K Epp
Introduction
Janet K Epp is a prominent inventor based in Indianapolis, IN (US). She has made significant contributions to the field of biotechnology, particularly in the development of recombinant DNA technologies. With a total of 5 patents, her work focuses on enhancing antibiotic production through innovative genetic engineering techniques.
Latest Patents
One of her latest patents involves recombinant DNA vectors encoding a 4'-O-isovaleryl acylase derived from the carE gene of Streptomyces thermotolerans. This invention has been pivotal in constructing recombinant DNA expression vectors. The carE gene encodes 4'-O-isovaleryl acylase activity, which is crucial in the biosynthesis of various useful antibiotics. This gene can be utilized to create recombinant cells that not only produce the acylase enzyme more efficiently but also generate novel antibiotic compounds. Another significant patent pertains to the carbomycin biosynthetic gene, designated carG. The carG gene, also isolated from Streptomyces thermotolerans, is essential for the biosynthesis of the 16-member cyclic lactone of carbomycin. This gene can similarly be employed to develop recombinant cells with enhanced capabilities to produce carbomycin and other innovative antibiotic compounds.
Career Highlights
Janet K Epp is currently employed at Eli Lilly and Company, where she continues to advance her research in biotechnology. Her work has been instrumental in the development of new antibiotics, addressing critical health challenges.
Collaborations
Throughout her career, Janet has collaborated with notable colleagues, including Brigitte E Schoner and Ramamoorthy Belagaje. These partnerships have fostered a collaborative environment that enhances innovation and research outcomes.
Conclusion
Janet K Epp's contributions to antibiotic production through her innovative patents and collaborations highlight her significant role in the field of biotechnology. Her work continues to pave the way for advancements in medical treatments and antibiotic development.