The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 1991
Filed:
May. 13, 1988
Applicant:
Inventors:
Janet K Epp, Indianapolis, IN (US);
Brigitte E Schoner, Monrovia, IN (US);
Assignee:
Eli Lilly and Company, Indianapolis, IN (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435183 ; 435 691 ; 435 711 ; 435 72 ; 435 91 ; 435119 ; 435169 ; 4351721 ; 4351723 ; 4352523 ; 43525235 ; 4353201 ; 435886 ; 536-71 ; 536 27 ; 935-9 ; 935 14 ; 935 22 ; 935 29 ; 935 38 ; 935 59 ; 935 60 ; 935 61 ; 935 66 ; 935 76 ;
Abstract
The carE gene of Streptomyces thermotolerans has been isolated and used to construct recombinant DNA expression vectors. The carE gene encodes 4'-O-isovaleryl acylase activity important in the biosynthesis of a number of useful antibiotics. The carE gene can be used not only to construct recombinant cells with an increased ability to produce the acylase enzyme but also to construct recombinant cells with the ability to produce novel antibiotic compounds.