Location History:
- St. Mellons, GB (2012 - 2015)
- Cardiff, GB (2005 - 2019)
- Barry, GB (2023)
Company Filing History:
Years Active: 2005-2023
Title: Innovations of Inventor Jane Sanders
Introduction
Jane Sanders is a prominent inventor located in Cardiff, GB, known for her groundbreaking contributions to the field of biochemistry and molecular biology. With an impressive portfolio of 15 patents, Sanders has made significant strides in understanding and manipulating the thyroid stimulating hormone receptor (TSHR), demonstrating her expertise and innovation in the life sciences.
Latest Patents
Among her latest acclaimed patents are those focused on mutant thyroid stimulating hormone receptors. One of her notable inventions is a mutant TSHR or fragment thereof, which comprises one or more mutations that enhance thermostability compared to the wild type TSHR. This invention highlights mutations located within the extracellular leucine-rich repeat domain or the transmembrane domain of the TSHR. The patented technology allows for the purification of the mutant TSHR while retaining its biological activity, making it valuable for therapeutic applications. Another significant patent involves isolated human anti-TSHR antibodies that bind to TSHR, effectively reducing ligand-induced stimulation without altering constitutive activity.
Career Highlights
Jane has made strides in the research community through her role at RSR Limited, where she leverages her scientific knowledge to further her innovative developments. Her work has contributed to advancements in understanding autoimmune responses related to TSHR and has potential therapeutic implications for related disorders.
Collaborations
Throughout her career, Jane has collaborated with esteemed colleagues such as Jadwiga Furmaniak and Bernard Rees Smith. These partnerships have allowed her to expand her research and refine her inventions further, fostering an environment of innovation and exploration within the field.
Conclusion
In summary, Jane Sanders stands out as a leading inventor with a rich background in biochemistry. Her latest patents reflect a significant advancement in the understanding of TSHR mutations and their applications in medicine. As she continues her work at RSR Limited, the impact of her inventions is set to revolutionize the field and improve therapeutic options for patients worldwide.