This inventor holds 2 USPTO granted patents. Top assignee: Other. Active years: 2001-2002.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
2 out of 834,570 Years Active: 2001-2002
Title: Jürgen Wolfrum: Innovator in Optical Detection and DNA Sequencing
Introduction
Jürgen Wolfrum is a notable inventor based in Rosdorf, Germany. He has made significant contributions to the fields of optical detection and DNA sequencing. With a total of 2 patents, his work has the potential to impact medical diagnostics and genetic research.
Latest Patents
Wolfrum's latest patents include a method for optical detection of analyte molecules in a natural biological medium. This innovative technique allows for the identification of individual tumor markers in undiluted blood plasma using fluorescent dyes. The method involves exposing blood plasma to pulsed diode laser radiation and detecting decay curves through time-correlated single photon counts. If the relative amount of fluorescent photons exceeds 0.3, a tumor marker is confirmed to be present.
Another significant patent is a process for sequencing an individual DNA molecule. This method utilizes a coated fiber point that binds with streptavidin and dyed copies of the DNA molecule. The detection of bonds is achieved through light coupling, which excites the dyed DNA to emit fluorescent light. The process allows for the decomposition of the DNA molecule base by exonucleases, enhancing the signal-to-noise ratio for individual molecule detection.
Career Highlights
Throughout his career, Jürgen Wolfrum has focused on developing advanced techniques for biological analysis. His innovative approaches have garnered attention in the scientific community, particularly for their applications in cancer detection and genetic sequencing.
Collaborations
Wolfrum has collaborated with Karl-Heinz Drexhage, contributing to the advancement of research in his field. Their partnership has led to the development of groundbreaking technologies that enhance the capabilities of optical detection and DNA sequencing.
Conclusion
Jürgen Wolfrum's contributions to the fields of optical detection and DNA sequencing exemplify the impact of innovative thinking in science. His patents reflect a commitment to advancing medical diagnostics and genetic research, paving the way for future discoveries.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile