Location History:
- Madison, CT (US) (2001)
- Guilford, CT (US) (2001 - 2013)
Company Filing History:
5 out of 305 
2 out of 41 
1 out of 10 Years Active: 2001-2013
Title: Jan W F Wasley: Innovator in Therapeutic Chemistry
Introduction
Jan W F Wasley is a notable inventor based in Guilford, CT (US), recognized for his contributions to therapeutic chemistry. He holds a total of 8 patents, showcasing his innovative approach to developing novel chemical compounds aimed at treating various disorders.
Latest Patents
Among his latest patents, Wasley has developed therapeutic pyrazoloquinoline derivatives. This invention provides a novel chemical series of formula I, along with methods for binding to the benzodiazepine site of the GABA receptor. It aims to modulate GABA and offers potential treatment options for GABA receptor-associated disorders. The general structure of formula I can exist in tautomeric forms. Additionally, he has created therapeutic pyrazolonaphthyridine derivatives, which also bind to the benzodiazepine site of the GABA receptor. This invention focuses on negatively modulating the α5 subtype of GABA, further contributing to the treatment of GABA receptor-associated disorders.
Career Highlights
Throughout his career, Jan W F Wasley has worked with prominent companies in the field, including Neurogen Corporation and Dart Neuroscience Ltd. His work has significantly impacted the development of therapeutic agents aimed at neurological conditions.
Collaborations
Wasley has collaborated with notable colleagues such as Xiao-shu He and Brian De Costa, contributing to the advancement of research in therapeutic chemistry.
Conclusion
Jan W F Wasley stands out as an influential inventor in the field of therapeutic chemistry, with a focus on innovative compounds that address critical health issues. His work continues to pave the way for advancements in treatment methodologies.