The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 30, 2013
Filed:
Nov. 18, 2010
Alan P. Kaplan, San Diego, CA (US);
Varsha Gupta, Encinitas, CA (US);
Jan W. F. Wasley, Guilford, CT (US);
Alan P. Kaplan, San Diego, CA (US);
Varsha Gupta, Encinitas, CA (US);
Jan W. F. Wasley, Guilford, CT (US);
Dart NeuroScience (Cayman) Ltd, Grand Cayman, KY;
Abstract
The invention provides a novel chemical series of formula I, as well as methods of use thereof for binding to the benzodiazepine site of the GABAreceptor and negatively modulating the α5 subtype of GABA, and use of the compound of formula I for the treatment of GABAreceptor associated disorders. The general structure of formula I is shown below: The invention further provides a method of modulation of one or more GABAsubtypes in an animal comprising administering to the animal an effective amount of a compound of formula (I).