Company Filing History:
Years Active: 1987
Title: Jan Kalter - Innovator in Pharmaceutical Chemistry
Introduction
Jan Kalter is a notable inventor based in Hazerswoude-Dorp, Netherlands. He has made significant contributions to the field of pharmaceutical chemistry, particularly in the development of processes for synthesizing important compounds.
Latest Patents
Kalter holds a patent for a process titled "Cephalosporin deoxygenation process." This innovative method involves the preparation of 7.beta.-acylamino-3-substituted-3-cephem-4-carboxylic acid compounds. The process requires reacting at temperatures ranging from -70°C to 0°C in an inert organic solvent, utilizing phosphorus pentachloride with a cephalosporin compound. The presence of an olefinic compound with specific characteristics is crucial for the reaction, allowing for the removal of chlorine through addition to a carbon-carbon double bond.
Career Highlights
Jan Kalter is associated with Gist-Brocades N.V., a company known for its advancements in biotechnology and pharmaceuticals. His work has contributed to the development of innovative solutions in the industry.
Collaborations
Kalter has collaborated with notable colleagues, including Jan Verweij and Herman H Grootveld. These partnerships have fostered a collaborative environment that enhances research and development efforts.
Conclusion
Jan Kalter's contributions to pharmaceutical chemistry, particularly through his patented processes, highlight his role as an innovator in the field. His work continues to influence advancements in drug development and synthesis.