Location History:
- Taipei, TW (2001 - 2013)
- Kaohsiung, TW (2011 - 2015)
Company Filing History:
6 out of 144 
2 out of 685 
1 out of 1 Years Active: 2001-2015
Title: Innovations and Contributions of Jan-Gowth Chang
Introduction
Jan-Gowth Chang is a prominent inventor based in Kaohsiung, Taiwan. He has made significant contributions to the field of biomedical research, particularly in the study of motor neuron diseases and developmental disorders. With a total of 9 patents to his name, Chang's work has the potential to impact therapeutic approaches in these areas.
Latest Patents
One of his latest patents is titled "Method of regulating the expression level of survival of motor neuron 1." This invention relates to a method of regulating the expression level of survival of motor neuron 1 (SMN1) by administering a therapeutically effective amount of ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) regulator along with a pharmaceutically acceptable carrier. Another notable patent is "hnRNP A1 knockout animal model and use thereof." This patent provides a nucleic acid construct comprising a genetically engineered heterogeneous nuclear ribonucleoprotein (hnRNP) A1 gene. It also describes a transgenic mouse model in which the expression of the hnRNP A1 gene has been disrupted, useful for studying the role of this gene in normal and disease states related to developmental disorders and muscular diseases.
Career Highlights
Jan-Gowth Chang has worked with esteemed institutions such as Kaohsiung Medical University and Academia Sinica. His research has focused on understanding the molecular mechanisms underlying various neurological conditions, contributing to advancements in medical science.
Collaborations
Chang has collaborated with notable colleagues, including Yuh-Jyh Jong and Hung Li. These partnerships have facilitated the exchange of ideas and expertise, enhancing the quality and impact of his research.
Conclusion
Jan-Gowth Chang's innovative work and patents reflect his dedication to advancing biomedical research. His contributions are poised to make a significant difference in the treatment of motor neuron diseases and developmental disorders.