The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 03, 2015
Filed:
Nov. 27, 2013
Applicant:
Kaohsiung Medical University, Kaohsiung, TW;
Inventors:
Yung-Fu Chang, Kaohsiung, TW;
Ting-Yuan Liu, Kaohsiung, TW;
Yuh-Jyh Jong, Kaohsiung, TW;
Jan-Gowth Chang, Kaohsiung, TW;
Assignee:
Kaohsiung Medical University, Kaohsiung, TW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01K 67/027 (2006.01); G01N 33/50 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
A61K 67/0276 (2013.01); G01N 33/5011 (2013.01); G01N 33/5088 (2013.01); G01N 22/6896 (2013.01); C12N 15/85 (2013.01); G01N 2800/28 (2013.01); G01N 2800/7042 (2013.01);
Abstract
A nucleic acid construct comprising a genetic engineered heterogeneous nuclear ribonucleoprotein (hnRNP) A1 gene is provided. A transgenic mouse in which the expression of hnRNP A1 gene has been disrupted is also provided. The mouse is useful for studying the role of hnRNP A1 gene in normal and disease states of a developmental disorder and muscular diseases. Therefore, a method of screening a compound for potential use in prevention and/or treatment of developmental disorder and muscular diseases is further provided.