The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2015
Filed:
Feb. 23, 2011
Applicants:
Yuh-jyh Jong, Kaohsiung, TW;
Shih-hsien Hsu, Kaohsiung, TW;
Jan-gowth Chang, Kaohsiung, TW;
Inventors:
Assignee:
KAOHSIUNG MEDICAL UNIVERSITY, Kaohsiung, TW;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/404 (2006.01); C12Q 1/37 (2006.01); A61K 31/7105 (2006.01); G01N 33/50 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/37 (2013.01); A61K 31/404 (2013.01); A61K 31/7105 (2013.01); G01N 33/5044 (2013.01); G01N 33/6896 (2013.01); G01N 2800/28 (2013.01); G01N 2800/2878 (2013.01);
Abstract
The present invention relates to a method of regulating the expression level of survival of motor neuron 1 (SMN1) comprising administering to a subject in need thereof a therapeutically effective amount of ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) regulator and a pharmaceutically acceptable carrier. The present invention also relates to a method of detecting enzyme activity of ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) in human fibroblasts comprising detecting protein expression level of survival of motor neuron 1 (SMN1).