Company Filing History:
Years Active: 2015-2023
Title: Innovations of Shih-Hsien Hsu
Introduction
Shih-Hsien Hsu is a notable inventor based in Kaohsiung, Taiwan. He has made significant contributions to the field of medical research, particularly in the development of innovative models and methods that have implications for understanding and treating various health conditions. With a total of 2 patents, his work continues to influence the scientific community.
Latest Patents
One of Hsu's latest patents is a liver lesion-mouse model. This model features a liver-specific ISX gene expression and p53 gene knockout transgenic mouse, wherein liver lesions develop after the mouse is fed a high-calorie diet. This invention provides a valuable tool for studying liver diseases and the effects of diet on liver health. Another significant patent is a method of regulating the expression level of survival of motor neuron 1 (SMN1). This method involves administering a therapeutically effective amount of ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) regulator along with a pharmaceutically acceptable carrier to subjects in need. Additionally, this invention includes a method for detecting the enzyme activity of UCHL1 in human fibroblasts by measuring the protein expression level of SMN1.
Career Highlights
Shih-Hsien Hsu is affiliated with Kaohsiung Medical University, where he conducts his research and develops his inventions. His work is characterized by a strong focus on genetic and molecular mechanisms that underlie various diseases, particularly those affecting the nervous system and liver.
Collaborations
Hsu collaborates with several colleagues, including Li-Ting Wang and Shen-Nien Wang, who contribute to his research efforts and help advance the projects he undertakes.
Conclusion
Shih-Hsien Hsu's innovative work in developing a liver lesion-mouse model and methods for regulating SMN1 expression showcases his commitment to advancing medical research. His contributions are vital for understanding complex health issues and developing potential therapeutic strategies.