Company Filing History:
Years Active: 2006
Title: Jamie H D Cate: Innovator in Ribosome Research
Introduction
Jamie H D Cate is a prominent inventor based in El Cerrito, California. He has made significant contributions to the field of molecular biology, particularly in understanding ribosome structures and their functions. His work has implications for drug design and the development of novel therapeutics.
Latest Patents
Jamie H D Cate holds a patent for "X-ray crystal structures of functional ribosome complexes containing transfer RNA and model messenger RNAs and methods of use." This patent details the 5.5 Angstrom resolution x-ray crystallographic structures of 70S ribosome complexes that include messenger RNA and transfer RNA (tRNA) or tRNA analogs. The resolution has been enhanced by fitting atomic resolution structures of the 30S and 50S subunits onto the 5.5 Angstrom electron density map. This enhanced structure reveals structural differences between the 70S complex and the individual 30S and 50S components. Furthermore, pharmacophore design to discover novel inhibitors or activators can be conducted using the enhanced 5.5 Angstrom 70S structure.
Career Highlights
Jamie H D Cate is affiliated with the University of California, where he continues to advance research in ribosome functionality and structure. His innovative work has garnered attention in the scientific community, contributing to a deeper understanding of ribosomal mechanisms.
Collaborations
Some of his notable collaborators include Harry F Noller and Marat M Yusupov. Their collective efforts have furthered the exploration of ribosomal structures and their biological significance.
Conclusion
Jamie H D Cate's contributions to ribosome research through his patent and collaborations highlight his role as an influential inventor in the field. His work continues to pave the way for advancements in molecular biology and therapeutic development.