Company Filing History:
1 out of 5,004 
1 out of 767 
Years Active: 2000-2006
Title: James T Fleming: Innovator in Cell-Based Logic and Gene Discovery
Introduction
James T Fleming is a notable inventor based in Knoxville, TN (US). He has made significant contributions to the fields of biotechnology and genetic engineering. With a total of 2 patents, his work focuses on innovative methods that enhance our understanding of cellular processes and gene expression.
Latest Patents
Fleming's latest patents include groundbreaking methods for cell-based combinatorial logic. This method involves providing genetically engineered cells that contain transcriptional units, which include genes and promoters. By applying a stimulus to the promoter, the expression of a gene product can be activated. The detection of an output signal corresponds to the presence of this gene product, allowing for the formation of logic gates through interconnected cells.
Another significant patent is related to the isolation of expressed genes in microorganisms. This invention optimizes the differential display technique to detect differential mRNA transcription from both pure cultures and soil-derived bacterial RNA. By using a model system with toluene induction in Pseudomonas putida F1, Fleming's method allows for the discovery of novel genes from environmental microbial communities without the biases of traditional culturing methods.
Career Highlights
Throughout his career, James T Fleming has worked with esteemed organizations, including the United States of America as Represented by the Secretary of the Air Force and the University of Tennessee Research Foundation. His innovative approaches have contributed to advancements in genetic research and biotechnology.
Collaborations
Fleming has collaborated with notable individuals in his field, including Gary S Sayler and Bruce Michael Applegate. These partnerships have further enriched his research and development efforts.
Conclusion
James T Fleming's contributions to biotechnology and genetic engineering are noteworthy. His innovative patents and collaborations reflect his commitment to advancing scientific knowledge and technology. His work continues to inspire future innovations in the field.