The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2006
Filed:
Sep. 06, 2001
Gary S. Sayler, Blaine, TN (US);
James T. Fleming, Knoxville, TN (US);
Bruce Applegate, West Lafayette, IN (US);
Michael L. Simpson, Knoxville, TN (US);
Gary S. Sayler, Blaine, TN (US);
James T. Fleming, Knoxville, TN (US);
Bruce Applegate, West Lafayette, IN (US);
Michael L. Simpson, Knoxville, TN (US);
University of Tennessee Research Foundation, Knoxville, TN (US);
Abstract
A method for cell-based combinatorial logic includes the steps of providing at least one genetically engineered cell, the genetically engineered cell having at least one transcriptional unit. The transcriptional unit includes a gene and a promoter, wherein application of a stimulus to the promoter results in the expression of a gene product. An energetic or chemical stimulus is applied to activate the promoter, wherein the detection of an output signal corresponds to the presence of a gene product. The cell can include a plurality of transcriptional units configured to form logic gates. The logic gates of a plurality of cells can be operably interconnected by release of output signals, such as chemical stimuli.