Whitinsville, MA, United States of America

James R Ladine


Average Co-Inventor Count = 4.0

ph-index = 1

Forward Citations = 8(Granted Patents)


Company Filing History:


Years Active: 2006-2012

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2 patents (USPTO):

Title: Innovations of James R. Ladine

Introduction

James R. Ladine is an accomplished inventor based in Whitinsville, MA (US). He holds 2 patents that reflect his significant contributions to the field of biotherapeutics and peptide analysis. His work has advanced the understanding and production of biomaterials, showcasing his innovative approach to complex scientific challenges.

Latest Patents

One of his latest patents focuses on enhanced biotherapeutic production using inhibitory RNA. This invention involves compositions, kits, systems, equipment, and protocols that utilize synthetic siRNA with a delivery facilitating moiety. These innovations improve bioprocesses that enhance the production of biomaterials by targeting various genes associated with undesirable properties in cells. The siRNA can effectively target genes that lead to non-optimal growth, heterogeneity, and the expression of non-desired proteins, among others.

Another notable patent by Ladine involves methods and kits useful for simplifying complex peptide mixtures. This invention provides methods and reagents for obtaining simplified mixtures of peptides from complex samples. The simplified samples are easier to analyze while still representing the original protein content. The methods utilize tagging moieties that react with specific amino acids, allowing for the isolation of peptides containing those amino acids.

Career Highlights

Throughout his career, James R. Ladine has worked with prominent companies in the biotechnology sector, including Dharmacon, Inc. and Thermo Finnigan LLC. His experience in these organizations has contributed to his expertise in biotherapeutics and peptide analysis.

Collaborations

Ladine has collaborated with notable professionals in his field, including William Marshall and Yuriy Fedorov. These collaborations have likely enriched his research and development efforts, leading to innovative solutions in biotherapeutics.

Conclusion

James R. Ladine's contributions to the fields of biotherapeutics and peptide analysis are significant, as evidenced by his patents and career achievements. His innovative work continues to impact the scientific community and advance the understanding of complex biological processes.

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