The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 25, 2012
Filed:
Jul. 11, 2008
James R. Ladine, Whitinsville, MA (US);
William S. Marshall, Boulder, CO (US);
Yuriy Fedorov, Superior, CO (US);
Christina Yamada, Boulder, CO (US);
James R. Ladine, Whitinsville, MA (US);
William S. Marshall, Boulder, CO (US);
Yuriy Fedorov, Superior, CO (US);
Christina Yamada, Boulder, CO (US);
Dharmacon, Inc., Lafayette, CO (US);
Abstract
Compositions, kits, systems, equipment, and protocols utilize synthetic siRNA having a delivery facilitating moiety in improved bioprocesses that enhance the production of biomaterials. The siRNA can target genes associated with the following: 1) deleterious vector derived genes; 2) genes that confer non-optimal growth or differentiation properties to the cells; 3) genes that can influence heterogeneity or post-translational modification pattern of the desirable gene product; 4) genes that highly express non-desired proteins; 5) genes that express proteins which interfere with purification of the desired protein; and 6) other genes that can interfere with the bioprocess.