James R Golke

Title: The Innovative Contributions of James R. Golke

Introduction

James R. Golke is a notable inventor based in Yorktown Heights, NY (US). He has made significant contributions to the field of immunoassays, with a focus on polypeptide-labeled analyte analogs. His work has led to advancements in highly sensitive methods for determining analyte concentrations in various samples.

Latest Patents

Golke holds a total of 3 patents. His latest patents include a method for preparing a polypeptide-labeled analyte analog for use in immunoassays. This innovative approach allows for the binding of the analog with a polypeptide partner, providing enzymatic activity such as ribonuclease or β-galactosidase activity. The method enhances the sensitivity of immunoassays, enabling the determination of analyte amounts in samples with unknown concentrations. The process involves bringing together a sample, the polypeptide-labeled analog, a specific antibody, a polypeptide partner, and a substrate that can be converted to a reporter molecule. The competitive binding of the polypeptide-labeled analyte analog to the antibody and polypeptide partner is crucial for the assay's effectiveness.

Career Highlights

Throughout his career, Golke has worked with several prominent companies, including Baker Instruments Corporation and Biopharma S.A. His experience in these organizations has contributed to his expertise in the development of innovative immunoassay methods.

Collaborations

Golke has collaborated with notable professionals in his field, including Peter R. Farina. These partnerships have facilitated the exchange of ideas and advancements in the realm of immunoassays.

Conclusion

James R. Golke's contributions to the field of immunoassays through his innovative patents and collaborations highlight his significant role as an inventor. His work continues to impact the way analytes are measured in various samples, showcasing the importance of innovation in scientific research.