James R Eshleman

Title: James R Eshleman: Innovator in Cancer Diagnostics

Introduction

James R Eshleman is a notable inventor based in Lutherville, MD (US). He has made significant contributions to the field of cancer diagnostics, particularly in relation to pancreatic cancer. With a total of 2 patents, Eshleman's work focuses on innovative methods for detecting genetic mutations and diagnosing diseases.

Latest Patents

Eshleman's latest patents include a diagnostic method using the PALB2 gene. This invention provides a method for detecting mutations in the PALB2 gene in pancreatic cancer patients and individuals with a family history of the disease. The methods also allow for diagnosing a predisposition to pancreatic cancer, predicting a patient's response to therapies, and treating the disease based on the presence of a PALB2 mutation or aberrant PALB2 gene expression. Another significant patent involves methods for the detection of nucleic acid differences. This invention enables the detection of small amounts of different nucleic acids in the presence of an excess of wild-type nucleic acids. It also includes methods for detecting infectious disease minority variants, forensic identification, cancer diagnosis, and monitoring disease progress.

Career Highlights

James R Eshleman is affiliated with The Johns Hopkins University, where he continues to advance research in cancer diagnostics. His work has been instrumental in developing methods that enhance the accuracy of cancer detection and treatment.

Collaborations

Eshleman has collaborated with prominent figures in the field, including Bert Vogelstein and Kenneth W Kinzler. These partnerships have contributed to the advancement of cancer research and diagnostics.

Conclusion

James R Eshleman's innovative contributions to cancer diagnostics, particularly through his patents, have the potential to significantly impact patient care and treatment outcomes. His work exemplifies the importance of research and innovation in the fight against cancer.