Location History:
- Gardiner, NY (US) (1991)
- Brookline, MA (US) (1996 - 2017)
Company Filing History:
4 out of 2,971 
2 out of 1,386 
1 out of 1,039 
Years Active: 1991-2017
Title: Innovations of James P. Butler
Introduction
James P. Butler is a notable inventor based in Brookline, MA (US), recognized for his contributions to the field of biological engineering. He holds a total of six patents, showcasing his innovative approach to scientific challenges. His work primarily focuses on understanding cellular mechanics and developing advanced biological assay platforms.
Latest Patents
One of Butler's latest patents is for Monolayer Stress Microscopy. This invention discloses systems, apparatus, devices, and methods that include determining traction forces exerted by a cellular monolayer on a substrate. It also involves determining internal forces within and between cells of the monolayer based on the traction forces. In certain embodiments, the method includes determining internal stresses within the cellular monolayer that act to balance the traction forces. Additionally, it may involve setting boundary conditions based on an optical field of view of the observed section of the monolayer. Another significant patent is for Deformable Platforms for Biological Assays. This platform includes a base substrate providing structural support, with at least one surface coated with position markers. It features a first deformable layer on top of the base substrate and a second deformable layer embedded with deformation markers.
Career Highlights
Throughout his career, James P. Butler has worked with prestigious institutions such as Harvard College and Brigham and Women's Hospital, Inc. His work has significantly advanced the understanding of cellular behavior and the development of innovative tools for biological research.
Collaborations
Butler has collaborated with notable colleagues, including Jeffrey J. Fredberg and George P. Topulos. Their combined expertise has contributed to the success of various research projects and innovations.
Conclusion
James P. Butler's contributions to the field of biological engineering through his patents and collaborations highlight his role as a leading inventor. His work continues to influence advancements in cellular mechanics and biological assays.