Company Filing History:
4 out of 850 
1 out of 84 
Years Active: 2006-2012
Title: Innovator Spotlight: James N. Topper and His Contributions to Medical Science
Introduction: James N. Topper, based in Los Altos, CA, is a prominent inventor with a significant impact on the field of biomedical research. With a total of four patents to his name, his work primarily focuses on understanding the role of secreted proteins in vascular endothelium, specifically through the identification and characterization of SCUBE molecules.
Latest Patents: Among his latest patents, Topper's groundbreaking invention relates to the identification of a family of secreted proteins in vascular endothelium. This invention delves into gene expression within vascular endothelial cells and highlights a novel gene family consisting of SCUBE1, SCUBE2, and SCUBE3. These SCUBE proteins are pivotal as they may contribute to various medical conditions, including cardiovascular disease, hemostasis, thrombosis, inflammatory disease, bone metabolism disorders, urinary bladder disorders, and breast disorders.
Career Highlights: Throughout his career, James N. Topper has been associated with distinguished companies in the pharmaceutical industry, including Millennium Pharmaceuticals Limited and Curagen Corporation. His extensive experience in research and development has positioned him as a leader in his field, especially in understanding the implications of vascular biology in human health.
Collaborations: Topper has collaborated with esteemed colleagues such as James E. Tomlinson and Ruey-Bing Yang. These partnerships have enhanced his research efforts and contributed to advancements in the understanding of endothelial cell biology and its associated disorders.
Conclusion: James N. Topper exemplifies the spirit of innovation within the biomedical field. His contributions through his patents and professional endeavors are critical in paving the way for new therapeutic strategies that may assist in the treatment of various health issues linked to cardiovascular and inflammatory diseases. His work not only highlights the importance of scientific inquiry but also the collaborative efforts necessary to drive advancements in medicine.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.