The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 03, 2012
Filed:
Dec. 18, 2008
Ruey-bing Yang, San Mateo, CA (US);
Chi Kin Domingos NG, San Francisco, CA (US);
James E. Tomlinson, Burlingame, CA (US);
Laszlo G. Komuves, San Francisco, CA (US);
James N. Topper, Los Altos, CA (US);
Keith E. Robison, Wilmington, MA (US);
Ruey-Bing Yang, San Mateo, CA (US);
Chi Kin Domingos Ng, San Francisco, CA (US);
James E. Tomlinson, Burlingame, CA (US);
Laszlo G. Komuves, San Francisco, CA (US);
James N. Topper, Los Altos, CA (US);
Keith E. Robison, Wilmington, MA (US);
Millennium Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
The invention relates to SCUBE molecules and generally to gene expression in vascular endothelial cells. The invention specifically relates to the discovery of a novel gene family containing the genes and proteins referred to herein as SCUBE1, SCUBE2 and SCUBE3 which can be expressed in endothelial cells. SCUBE proteins may be involved in the development of cardiovascular disease, hemostasis, thrombosis, inflammatory disease, bone metabolism disorders, urinary bladder disorders and breast disorders.