Company Filing History:

10 out of 4,770

Merck + Co., Inc.

patents

2 out of 2,405

Merck Sharp + Dohme Corp.

patents

where one patent can have more than one assignee

Years Active: 1986-2011

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11 patents (USPTO):Sort by Forward Citations

Abstract keywords

1. 7915407 - Process for {3-[2(R)-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3(S)-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4,5-dihydro-[1,2,4]-triazol-1-yl}phosphonic acid (2011-03-29),

2. 7807829 - [object Object] (2010-10-05),

3. 6395898 - Trans-glycosidation process for the synthesis of (2R, 2-alpha-R, 3a)-2-[1-(3,5-bis(trifluoromethyl)phenyl)ethoxy]-3-(4-fluorophenyl)-1,4-oxazine (2002-05-28),

4. 6320052 - Process for the preparation of leukotriene antagonists (2001-11-20),

5. 5958743 - Stereospecific bioconversion of benzyl acetoacetate to (1999-09-28),

6. 5665882 - Pyridyl ethylation of lactams (1997-09-09),

7. 5614632 - Process for the preparation of leukotriene anatgonists (1997-03-25),

8. 4883878 - Process for unsymmetrical dithioacetals and dithioketals (1989-11-28),

9. 4645854 - Process for preparing HMG-CoA reductase inhibitors with a (1987-02-24),

10. 4611067 - Process for the preparation of HMG-CoA reductase inhibitors and (1986-09-09),

11. 4582914 - Process for the preparation of HMG-CoA reductase inhibitors (1986-04-15),

Title: The Innovations of James M McNamara

Introduction

James M McNamara is a notable inventor based in Rahway, NJ (US), recognized for his contributions to pharmaceutical chemistry. He holds a total of 11 patents, showcasing his innovative spirit and dedication to advancing medical science. His work primarily focuses on compounds that have significant therapeutic applications.

Latest Patents

One of McNamara's latest patents involves a process for the preparation of a compound known as {3-[2(R)-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3(S)-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4,5-dihydro-[1,2,4]-triazol-1-yl}phosphonic acid. This compound is particularly valuable as a substance P (neurokinin-1) receptor antagonist, which is useful in treating emesis and inflammatory diseases. The invention also includes pharmaceutically acceptable salts of this compound, further enhancing its applicability in medical treatments.

Career Highlights

Throughout his career, McNamara has worked with prominent companies in the pharmaceutical industry, including Merck & Company, Inc. and Merck Sharp & Dohme Corporation. His experience in these organizations has allowed him to develop and refine his innovative ideas, contributing to the advancement of drug development and therapeutic solutions.

Collaborations

Some of McNamara's notable coworkers include Ralph P Volante and Thomas R Verhoeven. Their collaborative efforts have likely played a role in the successful development of various projects and patents.

Conclusion

James M McNamara's contributions to the field of pharmaceutical chemistry through his patents and collaborations highlight his significant impact on medical science. His innovative work continues to pave the way for advancements in treatment options for various health conditions.

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