The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2010
Filed:
Nov. 03, 2005
James Michael Mcnamara, Fanwood, NJ (US);
Louis Matty, Basking Ridge, NJ (US);
Jonathan D. Rosen, Brooklyn, NY (US);
James Michael McNamara, Fanwood, NJ (US);
Louis Matty, Basking Ridge, NJ (US);
Jonathan D. Rosen, Brooklyn, NY (US);
Merck & Co., Inc., Rahway, NJ (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The present invention is concerned with a process for the preparation of the compound {3-[2(R)-[(1R)-1-[3,5-bis(tri-fluoromethyl)phenyl]ethoxy]-3(S)-(4-fluorophenyl)-morpholin-4-yl]methyl]-5-oxo-4,5-dihydro-[1,2,4]-triazol-1-yl}phosphonic acid, and pharmaceutically acceptable salts thereof. This compound is useful as a substance P (neurokinin-1) receptor antagonist. In particular, the compound is useful e.g., in the treatment of emesis and inflammatory diseases.