James M Cregg

Title: The Innovative Journey of James M. Cregg

Introduction

James M. Cregg, a distinguished inventor from Claremont, CA, holds an impressive portfolio of 16 patents. His work primarily focuses on advanced biotechnological methods that enhance protein expression, showcasing his significant contributions to the scientific community.

Latest Patents

Cregg's most recent patents highlight innovative approaches to protein production. One of his notable inventions involves yeast promoters for protein expression, which details isolated nucleic acids, expression methods, host cells, expression vectors, and DNA constructs used for generating proteins. This patent specifically emphasizes nucleic acids isolated from pastons with promoter activity, along with methods that leverage these pastons to produce a variety of proteins and polypeptides. Another significant patent outlines methods for synthesizing heteromultimeric polypeptides in yeast using a haploid mating strategy. This method allows for the synthesis and secretion of recombinant hetero-multimeric proteins in mating-competent yeast, involving the transformation of two haploid cells to create diploid strains that produce functionally assembled proteins.

Career Highlights

Throughout his career, Cregg has made valuable contributions while collaborating with notable companies, including the Keck Graduate Institute and Alderbio Holdings LLC. His expertise in biotechnology has been pivotal in advancing methods for protein synthesis and expression.

Collaborations

James M. Cregg has worked alongside talented individuals such as Ilya I. Tolstorukov and John A. Latham. These collaborations have enhanced his research, leading to significant breakthroughs in the fields of genetic engineering and protein production.

Conclusion

With a robust array of patents and groundbreaking research in protein expression and synthesis, James M. Cregg continues to influence the biotechnological landscape. His innovative approaches not only expand the boundaries of science but also pave the way for future advancements in biotechnology.