James M Clomburg

This inventor holds 12 USPTO granted patents and 8 published patent applications, plus 1 CIPO patent and 3 EPO patents. Top assignees: William Marsh Rice University, Other. Active years: 2016-2025.

USPTO Granted Patents = 12 (Patent Applications = 8)

% Patents Active = 100.0

CIPO Patents = 1 (Patent Applications = 1)

EPO Patents = 3 (Patent Applications = 8)

Average Co-Inventor Count = 2.8

ph-index = 3

Forward Citations = 15(Granted Patents)

Location History:

Tampa, FL (US) (2022)
Houston, TX (US) (2016 - 2024)

Company Filing History:

6 out of 661

William Marsh Rice University

patents

6 out of 834,453

Other

patents

Years Active: 2016-2025

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12 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 12460234 - Synthesis of isoprenoids and derivatives (2025-11-04),

2. 12163177 - Modified fatty acid biosynthesis with ACP-dependent thiolases (2024-12-10),

3. 11913049 - Bioconversion of short-chain hydrocarbons to fuels and chemicals (2024-02-27),

4. 11781120 - Biosynthesis of polyketides (2023-10-10),

5. 11697830 - Iterative platform for the synthesis of alpha functionalized products (2023-07-11),

6. 11319562 - Modified fatty acid biosynthesis with ACP-dependent thiolases (2022-05-03),

7. 11186834 - Biosynthesis of products from 1-carbon compounds (2021-11-30),

8. 11046978 - Synthesis of isoprenoids and derivatives (2021-06-29),

9. 10633676 - Reverse beta oxidation pathway (2020-04-28),

10. 10450593 - Type II fatty acid synthesis enzymes in reverse β-oxidation (2019-10-22),

11. 9994881 - Functionalized carboxylic acids and alcohols by reverse fatty acid oxidation in engineered microbes (2018-06-12),

12. 9416364 - Reverse beta oxidation pathway (2016-08-16),

Title: The Innovative Contributions of James M. Clomburg

Introduction

James M. Clomburg is a notable inventor based in Tampa, FL (US), recognized for his significant contributions to the field of biochemistry and synthetic biology. With a total of 12 patents to his name, Clomburg has made strides in the synthesis of isoprenoids and the development of novel metabolic pathways.

Latest Patents

Clomburg's latest patents include groundbreaking work on the synthesis of isoprenoids and derivatives. This disclosure relates to the use of enzyme combinations or recombinant microbes to produce isoprenoid precursors, isoprenoids, and derivatives, including prenylated aromatic compounds. His innovative approach utilizes novel metabolic pathways that exploit Claisen, aldol, and acyloin condensations, offering alternatives to the natural mevalonate (MVA) pathway and the 1-deoxy-d-xylulose 5-phosphate (DXP) pathways. These methods promise improved carbon and energy efficiency compared to traditional pathways. Additionally, Clomburg has developed methods for modified fatty acid biosynthesis using ACP-dependent thiolases, enabling microorganisms to produce a variety of chemicals and fuels.

Career Highlights

Throughout his career, Clomburg has worked with esteemed institutions, including William Marsh Rice University. His research has focused on enhancing the efficiency of biochemical processes, contributing to advancements in sustainable chemical production.

Collaborations

Clomburg has collaborated with notable colleagues such as Ramon Gonzalez and Seokjung Cheong, further enriching his research endeavors and expanding the impact of his work.

Conclusion

James M. Clomburg's innovative contributions to the field of biochemistry and synthetic biology highlight his role as a leading inventor. His work continues to influence the development of sustainable methods for chemical production, showcasing the importance of innovation in addressing modern challenges.