This inventor holds 2 USPTO granted patents and 1 published patent application. Top assignees: The University of Texas System, Health Research, Inc.. Active years: 1991-2008.
Company Filing History:
2 out of 5,633 
1 out of 313 Years Active: 1991-2008
Title: James L. Murray: Innovator in Immunogenic Peptides and Monoclonal Antibodies
Introduction
James L. Murray is a notable inventor based in Houston, Texas, recognized for his contributions to the fields of immunology and biochemistry. He holds 2 patents that focus on innovative methods and products aimed at enhancing immune responses.
Latest Patents
One of his latest patents is titled "Method for identifying and designing immunogenic peptides." This invention provides a method for identifying peptides that can increase a cytotoxic T lymphocytes (CTL) response to an antigen. The method involves comparing the amino acid sequences of the VH and/or VL portions of an anti-idiotypic monoclonal antibody with those of an antigen to identify regions of homology. This process further identifies an HLA binding motif within a homologous region, defining a peptide sequence useful for stimulating a CTL response. Additionally, the patent includes peptides identified by this method and outlines a method for using these peptides to stimulate a CTL response in individuals.
Another significant patent by Murray is related to "Monoclonal antibodies binding platinum complexes." This invention pertains to monoclonal antibodies that specifically bind to platinum (II) complexes. The antibodies are produced by hybridoma cell lines, which result from the fusion of neoplastic cells with antibody-producing cells from animals immunized against platinum (II) complexes. The patent details various hybridoma strains and emphasizes the production of monoclonal antibodies that can compete with existing antibodies.
Career Highlights
James L. Murray has worked with esteemed organizations such as the University of Texas System and Health Research, Inc. His work has significantly impacted the development of therapeutic strategies in immunology.
Collaborations
Murray has collaborated with notable individuals in his field, including Michael G. Rosenblum and Peter J. Kelleher. Their joint efforts have contributed to advancements in the understanding and application of immunogenic peptides and monoclonal antibodies.
Conclusion
James L. Murray's innovative work in immunogenic peptides and monoclonal antibodies showcases his commitment to advancing medical science. His patents reflect a deep understanding of immunology and a dedication to improving therapeutic outcomes.