Company Filing History:
2 out of 310 
1 out of 884 
Years Active: 2012-2025
Title: James L. Mohler: Innovator in Prostate Cancer Research
Introduction
James L. Mohler is a notable inventor based in Buffalo, NY (US), recognized for his contributions to the field of prostate cancer treatment. With a total of 2 patents, he has made significant strides in developing innovative solutions for combating malignant cell growth.
Latest Patents
Among his latest patents, Mohler has developed coumarin-modified androgens for the treatment of prostate cancer. This invention includes androstane and dihydrotestosterone compounds that are functionalized with carbocyclic or heterocyclic groups, which may be saturated or unsaturated. These compounds are designed to inhibit the growth of malignant and hyperplastic cells, providing potential treatments for diseases associated with such growth, including prostate cancer. Additionally, he has patented a novel steroid 5α-reductase enzyme termed SRD5AIII. This enzyme, with an estimated molecular weight of 37 kDa, converts testosterone to dihydrotestosterone at a pH of about 7.0. His work also includes methods for identifying inhibitors of SRD5AIII and detecting androgen-stimulated prostate cancer through prostate biopsy analysis.
Career Highlights
Throughout his career, Mohler has worked with reputable organizations such as Health Research, Inc. and the University of Kentucky Research Foundation. His research has focused on advancing the understanding and treatment of prostate cancer, contributing to the medical community's efforts in this critical area.
Collaborations
Some of his notable coworkers include Michael V. Fiandalo and David Watt, who have collaborated with him on various research projects aimed at improving cancer treatment methodologies.
Conclusion
James L. Mohler's innovative work in the field of prostate cancer research highlights his commitment to advancing medical science. His patents and collaborations reflect a dedication to finding effective treatments for malignant cell growth, making a significant impact in the fight against cancer.