Company Filing History:
22 out of 1,820 
17 out of 143 
1 out of 3,435 
Years Active: 1989-2016
Title: James L. Hartley: A Pioneer in Nucleic Acid Technologies
Introduction
James L. Hartley, based in Frederick, MD, is a remarkable inventor known for his significant contributions to the field of molecular biology. With an impressive portfolio of 40 patents, Hartley's innovations focus primarily on the synthesis and cloning of nucleic acid molecules. His work has paved the way for advanced biotechnological applications, making him a notable figure in the scientific community.
Latest Patents
Among his latest patents, Hartley's work titled "Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites" stands out. This invention provides innovative compositions and methods for recombinational cloning. The compositions include vectors equipped with multiple recombination sites and multiple topoisomerase recognition sites. These methods facilitate the simultaneous cloning of two or more different nucleic acid molecules, offering flexibility in genetic engineering. The invention allows for molecules to be either fused together or inserted into distinct sites within a vector. Furthermore, it provides for the linking or joining of various molecules and compounds, including chemical compounds, drugs, proteins, lipids, nucleic acids, and carbohydrates. Additionally, the invention encompasses host cells containing the nucleic acid molecules or prepared through its methods, as well as kits containing the relevant compositions, host cells, and nucleic acid molecules, to assist in the synthesis of nucleic acids.
Career Highlights
Throughout his career, Hartley has been associated with reputable companies, notably Life Technologies Corporation and Invitrogen Corporation. He has played a crucial role in the advancement of technologies that are essential for modern genetic research and application.
Collaborations
James has collaborated with esteemed colleagues, including Michael A. Brasch and Gary F. Temple. These partnerships have fostered an environment of shared knowledge and innovative thinking, contributing to the development of groundbreaking technologies in molecular cloning and nucleic acid synthesis.
Conclusion
James L. Hartley's contributions to the field of molecular biology are significant, with his numerous patents reflecting his innovative spirit and dedication to advancing scientific research. As a pioneer in nucleic acid technology, his work continues to influence biotechnological applications and inspire future generations of inventors and researchers.
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