James J Vredenburgh

Title: Innovations by James J Vredenburgh

Introduction

James J Vredenburgh is an accomplished inventor based in Chapel Hill, NC. He has made significant contributions to the field of pharmacogenomics, particularly in the evaluation of pharmaceutical metabolism. His work has implications for personalized medicine, especially in the context of chemotherapy.

Latest Patents

Vredenburgh holds a patent for "Methods for evaluating the ability to metabolize pharmaceuticals." This patent discloses methods for detecting variant genes associated with reduced metabolism of specific substrates, including CYP3A4 and CYP3A5. The genotyping methods he developed identify polymorphisms linked to reduced metabolism of chemotherapeutic agents, such as cyclophosphamide and BCNU. Additionally, his patent includes novel polymorphic nucleic acid molecules that are useful in these methods.

Career Highlights

Throughout his career, Vredenburgh has worked with notable organizations, including Genaissance Pharmaceuticals, Inc. and Duke University. His experience in these institutions has allowed him to advance his research and contribute to the understanding of drug metabolism.

Collaborations

Some of his notable coworkers include Marco Guida and Jeff Hall. Their collaboration has likely enriched the research environment and fostered innovative approaches in their respective fields.

Conclusion

James J Vredenburgh's work in pharmacogenomics and his patent contributions highlight the importance of understanding genetic variations in drug metabolism. His innovations pave the way for advancements in personalized medicine and improved therapeutic outcomes.