James Italia

Title: Innovations of James Italia

Introduction

James Italia is an accomplished inventor based in Brighton, MA (US). He has made significant contributions to the field of biotechnology, holding a total of 4 patents. His work focuses on advancing the understanding and application of protein engineering.

Latest Patents

One of his latest patents is titled "Genetically encoded tyrosine sulfation of proteins in eukaryotes." This patent describes an engineered tyrosyl-tRNA synthetase/tRNA pair that co-translationally incorporates O-sulfotyrosine in response to UAG codons in mammalian cells. This innovative platform enables the recombinant expression of eukaryotic proteins that are homogeneously sulfated at chosen sites. Another notable patent is the "Universal platform for genetic code expansion." This patent outlines methods and compositions for selecting and identifying orthogonal aminoacyl synthetase-tRNA pairs, which are used to incorporate unnatural amino acids in a site-specific manner in proteins. Specifically, it describes a novel tryptophanyl synthetase-tRNA pair that functions as both an opal and amber suppressor, allowing for the incorporation of tryptophan analogs into proteins.

Career Highlights

James Italia is currently employed at The Trustees of Boston College, where he continues to push the boundaries of protein engineering. His work has garnered attention in the scientific community, contributing to advancements in biotechnology and molecular biology.

Collaborations

James collaborates with fellow researcher Abhishek Chatterjee, enhancing the scope and impact of their innovative projects.

Conclusion

James Italia's contributions to the field of biotechnology through his patents and research at The Trustees of Boston College highlight his role as a leading inventor in protein engineering. His work continues to pave the way for future innovations in the field.