The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2025
Filed:
Jul. 21, 2020
Applicant:
Trustees of Boston College, Chestnut Hill, MA (US);
Inventors:
Abhishek Chatterjee, Brookline, MA (US);
James Italia, Brighton, MA (US);
Assignee:
Trustees of Boston College, Chestnut Hill, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/00 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/93 (2013.01); C12P 21/00 (2013.01); C12Y 601/01002 (2013.01);
Abstract
Methods and compositions are described for selecting and identifying orthogonal aminoacyl synthetase-tRNA pairs and their use to incorporate unnatural amino acids in a site-specific manner in proteins. Specifically described is a noveltyrptophanyl synthetase-tRNA pair that functions as both an opal and amber suppressor and that incorporates tryptophan analogs into proteins.