Location History:
- Harbor City, CA (US) (1986)
- Torrance, CA (US) (1991)
- Gardena, CA (US) (1993)
- San Jose, CA (US) (2009)
- Silver Spring, MD (US) (2010 - 2017)
- Ontario, CA (US) (2021)
- Chino Hills, CA (US) (2023)
- Bethesda, MD (US) (2019 - 2024)
Company Filing History:
10 out of 3,539 
6 out of 832,843 Years Active: 1986-2025
Title: The Innovative Contributions of James C Yang
Introduction
James C Yang is a prominent inventor based in Bethesda, MD, known for his significant contributions to the field of cancer research. With a total of 17 patents to his name, Yang has made remarkable strides in developing innovative therapies and diagnostic methods for cancer treatment.
Latest Patents
Among his latest patents, Yang has developed anti-mutated KRAS T cell receptors. This invention includes an isolated or purified T cell receptor (TCR) that has antigenic specificity for an HLA-A11-restricted epitope of mutated Kirsten rat sarcoma viral oncogene homolog (KRAS), Neuroblastoma RAS Viral (V-Ras) Oncogene Homolog (NRAS), or Harvey Rat Sarcoma Viral Oncogene Homolog (HRAS). The patent also covers related polypeptides, proteins, nucleic acids, recombinant expression vectors, host cells, and pharmaceutical compositions. Additionally, it discloses methods for detecting cancer in mammals and methods for treating or preventing cancer. Another significant patent is for anti-thyroglobulin T cell receptors, which includes a synthetic T cell receptor (TCR) with antigenic specificity for an HLA-A2-restricted epitope of thyroglobulin (TG). This patent also encompasses related polypeptides, proteins, nucleic acids, and pharmaceutical compositions, along with methods for cancer detection and treatment.
Career Highlights
James C Yang has had a distinguished career, working at the National Institutes of Health, a component of the US Department of Health & Human Services. His work has been pivotal in advancing cancer research and developing innovative therapeutic approaches.
Collaborations
Throughout his career, Yang has collaborated with notable colleagues, including Qiong J Wang and Zhiya Yu. These collaborations have contributed to the success of his research and the development of his patents.
Conclusion
James C Yang's innovative work in cancer research and his numerous patents highlight his significant contributions to the field. His dedication to developing effective treatments and diagnostic methods continues to impact the medical community positively.