Location History:
- Bethesda, MD (US) (1979)
- Visalia, CA (US) (2007)
Company Filing History:
3 out of 96 
2 out of 832,843 Years Active: 1979-2025
Title: Innovations by James C Hamilton
Introduction
James C Hamilton is a notable inventor based in Visalia, CA (US). He holds a total of 5 patents that focus on advancements in RNA interference (RNAi) technology. His work has significant implications for the treatment of various diseases, including obesity and renal disorders.
Latest Patents
Hamilton's latest patents include innovative RNAi agents designed to inhibit the expression of specific genes. One of his key patents involves RNAi agents for inhibiting the expression of activin receptor-like kinase 7 (ALK7). This patent describes RNAi agents and compositions that can effectively inhibit the ALK7 gene, providing potential therapeutic benefits for conditions such as obesity and insulin resistance. Another significant patent focuses on RNAi agents for inhibiting the expression of complement component C3 (C3). This technology aims to treat diseases mediated by C3 gene expression, including IgA nephropathy and other complement-mediated renal diseases.
Career Highlights
Throughout his career, Hamilton has worked with various companies, including Arrowhead Pharmaceuticals, Inc. His contributions to the field of RNAi technology have positioned him as a key figure in the development of novel therapeutic strategies.
Collaborations
Hamilton has collaborated with notable professionals in his field, including Tao Pei and Jeffrey Carlson. These collaborations have further enhanced the impact of his research and innovations.
Conclusion
James C Hamilton's work in RNAi technology represents a significant advancement in the treatment of various diseases. His patents and collaborations highlight his contributions to the field and the potential for future innovations.