Company Filing History:
7 out of 7 
2 out of 806 
Years Active: 2021-2025
Title: James Barnaby Trager: Innovating Immunotherapy
Introduction
James Barnaby Trager, an esteemed inventor based in Albany, California, has made significant contributions to the field of immunotherapy. With a total of seven patents credited to his name, Trager is recognized for his innovative approaches that enhance cancer treatments through cutting-edge technology.
Latest Patents
Among Trager's latest patents is the development of CD19-directed chimeric antigen receptors and their applications in immunotherapy. This technology is notable for comprising immune cell-based compositions, particularly those utilizing natural killer (NK) cells. The embodiments include humanized anti-CD19 binding portions that exhibit increased effectiveness in expression and cytotoxicity. Trager also pioneered methods for employing these engineered immune cells in immunotherapy, showcasing his commitment to advancing cancer treatment.
In addition, he has developed compositions that involve immune cells containing truncated NKG2D chimeric receptors. These NK cells are engineered to enhance their targeting abilities toward cancerous cells or those affected by infectious diseases. The inventions relate to improved cytotoxic effects and therapeutic methodologies aimed at treating various diseases, emphasizing Trager's pivotal role in this field.
Career Highlights
James Barnaby Trager has had an impactful career, including affiliations with notable organizations such as Nkarta, Inc. and the National University of Singapore. His work has significantly influenced the landscape of immunotherapy, reinforcing the importance of innovative solutions in medical research and clinical applications.
Collaborations
Throughout his career, Trager has collaborated with other talented individuals, including Alexandra Leida, Liana Lazetic, and Chao Guo. These partnerships have fostered creativity and have led to the development of groundbreaking technologies that have the potential to transform patient outcomes in immunotherapy.
Conclusion
James Barnaby Trager stands out as a remarkable inventor within the realm of immunotherapy. His extensive work in developing innovative patents continues to inspire advancements in medical technology and treatment methodologies. As he progresses in his career, Trager's contributions are sure to leave an indelible mark on the field, showcasing the transformative power of invention in healthcare.