James B hOYING

Title: Innovations of James B. Hoying in Bone Grafting Technology

Introduction

James B. Hoying is an accomplished inventor based in Manchester, NH (US). He has made significant contributions to the field of biomedical engineering, particularly in the area of bone grafting. His innovative work focuses on creating living bone grafts that closely mimic natural bone repair processes.

Latest Patents

James B. Hoying holds a patent for a groundbreaking invention titled "Bone graft and methods of fabrication and use." This patent describes a living bone graft that includes a biofabricated graft core made of demineralized bone matrix and a carrier, along with a pre-vascularized shell that partially enrobes the graft core. The pre-vascularized shell contains isolated, intact adipose-derived microvessel fragments, mesenchymal stem cells, and collagen. The bone grafts are designed to include stromal cells that differentiate and microvessels that inosculate, providing a functional microvasculature that approximates native bone repair as the graft matures in the patient. Additionally, the patent outlines methods for fabricating bespoke, living, vascularized bone grafts and treating segmental bone defects in patients.

Career Highlights

James B. Hoying is associated with Advanced Solutions Life Sciences, LLC, where he continues to advance his research and development efforts. His work has garnered attention for its potential to revolutionize the treatment of bone injuries and defects.

Collaborations

James collaborates with various professionals in the field, including his coworker Sarah Moss, to further enhance the impact of his innovations.

Conclusion

James B. Hoying's contributions to bone grafting technology represent a significant advancement in medical science. His innovative approach to creating living bone grafts has the potential to improve patient outcomes in bone repair and regeneration.