Chapel Hill, NC, United States of America

James A Raleigh



Average Co-Inventor Count = 2.7

ph-index = 3

Forward Citations = 20(Granted Patents)


Company Filing History:


Years Active: 1997-2015

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4 patents (USPTO):Explore Patents

Title: Innovations of James A. Raleigh in Tissue Hypoxia Detection

Introduction

James A. Raleigh is an accomplished inventor based in Chapel Hill, NC (US). He has made significant contributions to the field of medical imaging and treatment through his innovative inventions. With a total of 4 patents, Raleigh's work focuses on the non-invasive detection of tissue hypoxia, which is crucial for diagnosing various medical conditions.

Latest Patents

Raleigh's latest patents include groundbreaking inventions that utilize weakly basic 2-nitroimidazoles for the non-invasive detection of tissue hypoxia. One of his notable inventions incorporates weakly basic substituents such as pyrrolidine, piperidine, piperazine, and azapane moieties in halogenated 2-nitromidazoles. This innovation allows for the detection of cellular hypoxia in both normal and malignant tissues, with applications in positron emission tomography, magnetic resonance spectroscopy, and magnetic resonance imaging. Another significant patent features hypoxia-selective, weakly basic 2-nitroimidazole delivery agents that contain a secondary basic nitrogen atom and a linker with therapeutic agents. These compounds are particularly useful in boron neutron capture therapy (BNCT) for treating hypoxic conditions, including cancer, inflammation, and ischemia.

Career Highlights

James A. Raleigh is currently associated with Natural Pharmacia International, Inc., where he continues to develop innovative solutions in the medical field. His work has garnered attention for its potential to improve diagnostic and therapeutic techniques.

Collaborations

Raleigh collaborates with esteemed colleagues such as David Y-w Lee and Xiao-Shen Ji, contributing to a dynamic research environment that fosters innovation and discovery.

Conclusion

James A. Raleigh's contributions to the field of tissue hypoxia detection through his innovative patents highlight his role as a leading inventor in medical technology. His work not only advances scientific understanding but also has the potential to significantly impact patient care.

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