Location History:
- Croton-on-Hudson, NY (US) (1981 - 1982)
- Croton-on-Hudson both of, NY (US) (1982)
Company Filing History:
Years Active: 1981-1982
Title: The Innovations of James A. Grattan
Introduction
James A. Grattan is a notable inventor based in Croton-on-Hudson, NY (US). He has made significant contributions to the field of chemistry, particularly in the synthesis of folic acid derivatives. With a total of 4 patents to his name, Grattan's work has had a meaningful impact on various applications in the medical and scientific communities.
Latest Patents
One of Grattan's latest patents involves a process for the preparation of folic acid derivatives. These derivatives, such as radiolabeled pteroyltyrosine, are synthesized from either pteroic acid or through the direct condensation of 6-formylpterin with p-aminobenzoyltyrosine methyl ester. The radioiodinated derivatives produced are particularly useful in competitive protein binding and radioimmunoassays of folate compounds. This innovative approach enhances the utility of folic acid derivatives in various diagnostic applications.
Career Highlights
Throughout his career, Grattan has worked with prominent companies, including Baker Instruments Corporation and Union Carbide Corporation. His experience in these organizations has allowed him to develop and refine his innovative ideas, contributing to advancements in the field of chemistry.
Collaborations
Grattan has collaborated with various professionals in his field, including his coworker Peter R. Farina. These collaborations have fostered an environment of innovation and have led to the successful development of new technologies and methodologies.
Conclusion
James A. Grattan's contributions to the field of chemistry, particularly through his patents on folic acid derivatives, showcase his innovative spirit and dedication to scientific advancement. His work continues to influence the medical and scientific communities, highlighting the importance of innovation in addressing complex challenges.