Company Filing History:
2 out of 321 
2 out of 4 Years Active: 2014-2015
Title: Innovator in Autoimmune Therapeutics: Jae Kyeong Byun
Introduction
Jae Kyeong Byun is a distinguished inventor based in Chungcheongbuk-do, South Korea. With a strong focus on therapeutic innovations, he has contributed significantly to the field of autoimmune disease treatment through his inventive work.
Latest Patents
Jae Kyeong Byun holds two notable patents, both aimed at addressing the challenges associated with autoimmune diseases.
1. **Dual Antagonist for TNF-α and IL-21 for Preventing and Treating Autoimmune Diseases**: This invention pertains to a TNFR2-IL21R fusion protein that acts as a double-antagonist targeting TNF-alpha (α) and IL-21. This composition, crucial in combating autoimmune rheumatoid arthritis, exhibits the ability to reduce inflammatory cytokine secretion and enhance anti-inflammatory cytokine levels, ultimately improving therapeutic outcomes compared to single-protein treatments. The fusion protein has demonstrated remarkable efficacy in reducing symptoms in a collagen-induced arthritis mouse model, marking it a promising agent in autoimmune disease treatment.
2. **TNF-A and TWEAK Dual Antagonist for the Prophylaxis and Treatment of Autoimmune Diseases**: This innovation describes a TNFR2-TWEAKR fusion protein functioning as a double-antagonist to TNF-α and TWEAK. The invention focuses on its ability to decrease IL-17 secretion while promoting IL-10 secretion from Treg cells when administered to Th17 cells. Similar to his first invention, this fusion protein has also shown pronounced treatment effects in murine models of autoimmune rheumatoid arthritis.
Career Highlights
Jae Kyeong Byun has made substantial contributions to scientific research through his work at reputable institutions, including the Korea Research Institute of Bioscience and Biotechnology and the Industry-Academic Cooperation Foundation, and the Catholic University of Korea. His research endeavors have laid the groundwork for innovative approaches to treating challenging autoimmune conditions.
Collaborations
Throughout his career, Jae Kyeong Byun has collaborated with esteemed colleagues, including Young Woo Park and Ki Won Jo. These collaborations have fostered a synergistic environment for research and innovation, enhancing the impact of his inventions in the field.
Conclusion
Jae Kyeong Byun exemplifies the spirit of innovation within the realm of autoimmune disease therapeutics. His patents not only address critical medical needs but also pave the way for future advancements in treatment methodologies, showcasing the potential of targeted biotherapeutics to transform patient care.