Jae-Ick Sim

Title: Jae-Ick Sim: Innovator in Biotechnology

Introduction

Jae-Ick Sim is a prominent inventor based in Icheon-si, South Korea. He has made significant contributions to the field of biotechnology, particularly in the development of microorganisms and gene expression technologies. With a total of 5 patents, his work has had a notable impact on various applications in the industry.

Latest Patents

Among his latest patents, Jae-Ick Sim has developed a promoter that includes at least one polynucleotide selected from the group consisting of SEQ ID NOS: 1 to 7. This invention encompasses an expression cassette, a vector, and a host cell that utilizes the vector, along with a method for expressing a gene using the host cell. Additionally, he has created a microorganism that produces 5'-xanthylic acid. This microorganism is derived from treating KCCM 10488, which produces 5'-xanthylic acid as a parent strain, with UV radiation and mutation derivatives such as N-methyl-N′-nitro-N-nitrosoguanidine (NTG). This innovation enhances the biosynthesis of N5-N10-tetrahydrofolate, facilitating the accumulation of 5'-xanthylic acid in culture medium at high yield and concentration rates during fermentation.

Career Highlights

Jae-Ick Sim has worked with notable companies such as CJ Cheiljedang Corporation and CJ Corporation. His experience in these organizations has allowed him to apply his innovative ideas in practical settings, contributing to advancements in biotechnology.

Collaborations

Throughout his career, Jae-Ick Sim has collaborated with esteemed colleagues, including Young-Hoon Park and Jeong-Hwan Kim. These partnerships have fostered a collaborative environment that encourages the exchange of ideas and expertise.

Conclusion

Jae-Ick Sim's contributions to biotechnology through his patents and collaborations highlight his role as an influential inventor in the field. His work continues to pave the way for advancements in gene expression and microbial production technologies.