Jacques Nunes

Title: Jacques Nunes: Innovator in Immunology

Introduction

Jacques Nunes, based in Marseilles, France, is an accomplished inventor known for his contributions to the field of immunology. With a total of seven patents to his name, he has made significant advancements in understanding immune responses and therapies.

Latest Patents

Among his notable inventions is a patent titled "Antibodies directed against ICOS and uses thereof." This invention provides antibodies that target ICOS, or a derivative thereof, effectively neutralizing its engagement on T regulatory cells (Treg). By inhibiting the fixation between ICOS and ICOS-L, these antibodies abrogate the proliferation of Treg induced by plasmacytoid dendritic cells. Furthermore, this invention also promotes the production of IL-10 and IFN-γ, induces proliferation of CD4- T cells, reduces the proliferation of conventional T cells (Tconv), and enhances the immunosuppressive functions of Treg.

Career Highlights

Jacques Nunes has had a distinguished career, working with esteemed research institutions such as the Institut Jean Paoli & Irene Calmettes and Centre Léon Bérard. His experience in these organizations has allowed him to further his research and refine his innovations in the immunology field.

Collaborations

Throughout his career, Jacques has collaborated with notable professionals, including Daniel Olive and Julien Faget. These partnerships have enriched his research and contributed to his success as an inventor.

Conclusion

In summary, Jacques Nunes has established himself as a prominent figure in immunology through his inventive work and collaborations. His patents not only advance scientific knowledge but also open new avenues for potential therapies in immunological disorders.