Company Filing History:
4 out of 13 
3 out of 822 
1 out of 1 Years Active: 2014-2020
Title: Innovator Profile: Jacobus A J Den Hartog
Introduction
Jacobus A J Den Hartog, a prominent inventor based in Hoofddorp, Netherlands, is known for his significant contributions to the field of pharmaceutical sciences. With four patents to his name, he has dedicated his career to developing innovative solutions for complex medical challenges.
Latest Patents
Among Den Hartog's most recent inventions are his patents related to fused heterocyclic derivatives as S1P modulators. These derivatives exhibit affinity for S1P receptors and hold promise for the treatment of diseases where S1P receptors play a crucial role. The compounds developed are useful for preparing medicaments aimed at treating and preventing conditions associated with S1P signaling regulation. Specifically, his work on these fused heterocyclic derivatives focuses on their potential to address cognitive disorders, age-related cognitive decline, and dementia, particularly as agonists of the S1P5 receptor.
Career Highlights
Throughout his career, Jacobus A J Den Hartog has held roles at leading pharmaceutical companies, including AbbVie B.V. and AbbVie Inc. His experience in these esteemed organizations reflects his expertise in drug development and innovation. Den Hartog's dedication to advancing pharmaceutical research is evident from his successful patent applications.
Collaborations
In the pursuit of his innovative work, Den Hartog has collaborated with notable colleagues such as Pieter Smid and Wouter I Iwema Bakker. These partnerships have contributed to the sharing of knowledge and insights, ultimately enhancing the development of groundbreaking pharmaceutical compounds.
Conclusion
Jacobus A J Den Hartog stands out as a dedicated inventor whose work in the field of S1P modulators has the potential to impact the treatment of significant medical conditions. His contributions to pharmaceutical innovation continue to inspire new approaches to healthcare challenges, reflecting the importance of collaboration and creativity in the pursuit of scientific advancement.