Jaakko A Uotila

Title: Jaakko A Uotila: Innovator in Pharmaceutical Composition

Introduction

Jaakko A Uotila is a notable inventor based in Espoo, Finland. He has made significant contributions to the field of pharmaceuticals, particularly in the development of innovative compositions for oral administration. With a total of 2 patents, Uotila's work has the potential to enhance the effectiveness and palatability of pharmaceutical products.

Latest Patents

Uotila's latest patents include a composition for the oral administration of pharmaceuticals. This invention relates to a new three-layered composition designed for pharmaceutical granules. The innermost layer consists of a substantially pure fat, the middle layer is a mixture of fat and polymer, and the outermost layer is again a substantially pure fat. This innovative composition produces a tasteless preparation, making it especially suitable for powders or mixtures, even when the pharmaceutical has an unpleasant taste. Additionally, the preparation maintains stability in mixtures and allows for the transport of pharmaceuticals past the stomach for release and absorption at the beginning of the small intestine.

Another significant patent by Uotila is for acetyl erythromycin stearate, a new antibiotic compound. This compound is readily absorbed from the alimentary tract and is not converted to an ineffective form by gastric acid, unlike some other erythromycin antibiotics. The compound is effective even when taken with food, enhancing its usability for patients. The preparation process involves reacting erythromycin base with acetyl halide in an organic solvent, followed by the formation of the stearate salt without isolating the ester.

Career Highlights

Jaakko A Uotila is associated with Orion-yhtyma Oy, a company known for its focus on pharmaceutical innovations. His work has contributed to advancements in drug formulations that improve patient experiences and outcomes.

Collaborations

Uotila has collaborated with notable colleagues, including Esko Veikko Marttila and Ilkka Larma, who have also contributed to the field of pharmaceuticals.

Conclusion

Jaakko A Uotila's innovative work in pharmaceutical compositions showcases his commitment to improving drug delivery and patient care. His patents reflect a deep understanding of the challenges in the pharmaceutical industry and offer promising solutions for future developments.