The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 1986
Filed:
Dec. 27, 1984
Martti L Marvola, Helsinki, FI;
Esko V Marttila, Helsinki, FI;
Jaakko A Uotila, Espoo, FI;
Aino K Pippuri, Espoo, FI;
Pekka J Kairisalo, Helsinki, FI;
Erkki J Honkanen, Vantaa, FI;
Orion-yhtyma Oy, Espoo, FI;
Abstract
The invention relates to a new antibiotic compound, acetyl erythromycin stearate having formula I ##STR1## The compound according to the invention is absorbed readily from the alimentary tract. Gastric acid does not convert the compound according to the invention to an uneffective form as is the case with some other erythromycin antibiotics. Absorbing is good also when the patient eats when taking the new medicine. The compound according to the invention is prepared by reacting erythromycin base with acetyl halide in an organic solvent in the presence of an acid acceptor. The stearate salt is prepared from the obtained ester without in between isolating the ester.