Company Filing History:
Years Active: 2021-2022
Title: Ivan Rosenberg: Innovator in Cyclic Dinucleotide Research
Introduction
Ivan Rosenberg is a prominent inventor based in Prague, Czech Republic. He has made significant contributions to the field of organic chemistry, particularly in the development of cyclic dinucleotides. With a total of four patents to his name, Rosenberg's work has the potential to impact various medical applications.
Latest Patents
Rosenberg's latest patents include innovative compounds that modulate the activity of the STING adaptor protein. One of his notable inventions is related to 3'3′-cyclic dinucleotides modified with a 3′-phosphonoalkyl bond. This invention can enhance the modulation of the STING adaptor protein, which plays a crucial role in immune response. Another significant patent involves 2'3′ cyclic dinucleotides with a phosphonate bond that activate the STING adaptor protein. This disclosure outlines their potential use in treating or preventing diseases modifiable by STING protein modulation, including cancer and various viral, allergic, and inflammatory diseases. Additionally, these compounds can serve as adjuvants in vaccines.
Career Highlights
Ivan Rosenberg is affiliated with the Institute of Organic Chemistry and Biochemistry, where he conducts his research. His work has garnered attention for its innovative approach to addressing complex biological challenges.
Collaborations
Rosenberg collaborates with notable colleagues, including Gabriel Birkus and Ondrej Pav. Their combined expertise contributes to the advancement of research in their field.
Conclusion
Ivan Rosenberg's contributions to cyclic dinucleotide research exemplify the intersection of innovation and practical application in medicine. His patents hold promise for future therapeutic developments.