This inventor holds 2 USPTO granted patents, plus 1 CIPO patent and 1 EPO patent. Top assignees: Centre National De La Recherche Scientifique, Commissariat a L'energie Atomique Et Aux Energies Alternatives, Université Joseph Fourier. Active years: 2017-2018.
Company Filing History:
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2 out of 112 Years Active: 2017-2018
Title: Isabel Ayala: Innovator in Isotopic Labeling
Introduction
Isabel Ayala is a prominent inventor based in Pont de Claix, France. She has made significant contributions to the field of isotopic labeling, particularly in the study of amino acids. With a total of 2 patents, her work has advanced the understanding of protein analysis.
Latest Patents
Isabel Ayala's latest patents include a process for the specific isotopic labeling of methyl groups of Valine (Val), Leucine (Leu), and Isoleucine (Ile). This innovative process involves introducing an acetolactate derivative in a medium containing bacteria that overexpress a protein. Another notable patent focuses on the specific isotopic labeling of these amino acids using a 2-alkyl-2-hydroxy-3-oxobutanoic acid, where the alkyl substituent is either ethyl or methyl. This invention is particularly useful for protein analysis, especially through NMR techniques.
Career Highlights
Throughout her career, Isabel has worked with esteemed organizations such as the Commissariat à l'Énergie Atomique et aux Énergies Alternatives and the Centre National de la Recherche Scientifique. Her work in these institutions has allowed her to develop and refine her innovative processes.
Collaborations
Isabel has collaborated with notable colleagues, including Olivier Hamelin and Pierre Gans. These partnerships have contributed to her success and the advancement of her research.
Conclusion
Isabel Ayala is a trailblazer in the field of isotopic labeling, with her patents paving the way for advancements in protein analysis. Her contributions continue to impact the scientific community positively.