The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 18, 2017

Filed:

Jan. 06, 2010
Applicants:

Pierre Gans, Voreppe, FR;

Jérôme Boisbouvier, Grenoble, FR;

Isabel Ayala, Pont de Claix, FR;

Olivier Hamelin, Champagnier, FR;

Inventors:

Pierre Gans, Voreppe, FR;

Jérôme Boisbouvier, Grenoble, FR;

Isabel Ayala, Pont de Claix, FR;

Olivier Hamelin, Champagnier, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07B 59/00 (2006.01); G01N 24/08 (2006.01); C12P 21/02 (2006.01); C07C 59/215 (2006.01);
U.S. Cl.
CPC ...
C07B 59/008 (2013.01); C07B 59/001 (2013.01); C07C 59/215 (2013.01); C12P 21/02 (2013.01); G01N 24/087 (2013.01); G01N 2458/15 (2013.01);
Abstract

The invention relates to a process for the specific isotopic labeling of Valine, Leucine and Isoleucine amino acids. The process of the invention uses a 2-alkyl-2-hydroxy-3-oxobutanoic acid in which the alkyl substituent in position 2 is ethyl or methyl. The invention can be used for the analysis of proteins, in particular by NMR.


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