Iqbal Siddiqi

Title: Iqbal Siddiqi: Innovator in Biochemical Measurement

Introduction

Iqbal Siddiqi is a notable inventor based in Geneva, Switzerland. He has made significant contributions to the field of biochemical measurement, holding a total of eight patents. His work focuses on innovative methods that enhance the accuracy and efficiency of biochemical assays.

Latest Patents

Among his latest patents is a method of measuring a co-enzyme. This method utilizes the action of the co-enzyme in the production of hydrogen peroxide associated with the reaction of a hydroxylase with a decoupling agent in the presence of air or oxygen. The hydrogen peroxide is subsequently determined by quantitatively breaking the carbon-fluorine bond of a fluorinated compound in the presence of peroxidase, followed by electrometric titration of the resulting ions. Another significant patent involves a system of reactants that includes an apo-enzyme useful in immunological applications. This quick and simple immunoassay technique is applicable for determining large molecules such as proteins and polynucleotides. It involves labeling competitive immunospecies with an enzyme as a signal generator, which can be converted to the corresponding apo-enzyme form. The regeneration of this enzyme, upon the addition of a suitable co-factor, is inhibited by complexation when the labeled species react with its immunopartner. The degree of complexation is ascertained by measuring the extent of regenerated activity.

Career Highlights

Iqbal Siddiqi has worked with prominent organizations, including Battelle Memorial Institute and Hoffmann-La Roche Inc. His experience in these institutions has allowed him to develop and refine his innovative techniques in biochemical measurement.

Collaborations

Throughout his career, Iqbal has collaborated with notable professionals such as Hans-Rudolf Wuhrmann and Jean Brochot. These collaborations have contributed to the advancement of his research and the successful implementation of his patented methods.

Conclusion

Iqbal Siddiqi's contributions to the field of biochemical measurement through his innovative patents and collaborations highlight his role as a significant inventor. His work continues to influence the development of efficient biochemical assays and measurement techniques.